Menu

Therapeutic Specialties

AISER specializes in key therapeutic areas. This focus allows us to provide scientific expertise, operational excellence, and close alignment with our clients' goals.

Ramaz Miraishvili Research Fellow

New Imaging Technique May Enhance Accuracy of Cancer Surgery

Use of a chemofluorescence technique may allow surgeons to visualize, in real time, cancerous tissue, thereby increasing the precision of their resections, according to animal study findings presented Tuesday at the National Meeting of the American Chemical Society in Philadelphia.

Read more: New Imaging Technique May Enhance Accuracy of Cancer Surgery

Plasma DNA More Reliable Than CEA for Detecting Recurrent Esophageal Cancer

Elevated free plasma DNA is a reliable indicator of recurrent esophageal cancer, more so than carcinoembryonic antigen (CEA), and is able to detect recurrent disease in most patients before clinical evidence emerges. These findings come from a study by researchers at the University of Southern California, published in the July issue of the Journal of the American College of Surgeons.

Read more: Plasma DNA More Reliable Than CEA for Detecting Recurrent Esophageal Cancer

Earlier and More Aggressive LDL Lowering, or Better Approaches for Targeting High-Risk Individuals?

A new review by three renowned experts in cardiology suggests that efforts to treat elevated cholesterol levels are not exploiting the full potential of cholesterol-lowering strategies, and current approaches to treatment are simply doing "too little, too late. [1]" The evidence, say these experts, is strong enough to support even more aggressive use of lipid-lowering therapies and to intervene at earlier stages in the development of atherosclerosis.

Read more: Earlier and More Aggressive LDL Lowering, or Better Approaches for Targeting High-Risk Individuals?

Polyalkylimide Dermal Fillers Linked to Inflammatory and Granulomatous Reactions

Polyalkylimide implants (PAI) used as dermal fillers can infrequently result in delayed and recurrent chronic inflammatory and granulomatous reactions, according to the results of a study published in the May issue of the Archives of Dermatology.

Read more: Polyalkylimide Dermal Fillers Linked to Inflammatory and Granulomatous Reactions

High HBV Viral Load at Surgery Tied to Liver Cancer Return

In patients undergoing liver resection for hepatocellular carcinoma related to hepatitis B virus (HBV) infection, viral load at the time of surgery is predictive of hepatoma recurrence, according to Chinese researchers.

Read more: High HBV Viral Load at Surgery Tied to Liver Cancer Return

Recurrence Rare After Prostatectomy of Organ-Confined, Lower Grade Cancer

Men with organ-confined prostate cancer and a Gleason score of 6 or less very rarely have local or biochemical recurrence of disease 5 years after prostatectomy, according to study findings appearing in the July issue of Urology.

Read more: Recurrence Rare After Prostatectomy of Organ-Confined, Lower Grade Cancer

Tibolone Decreases Fracture, Breast Cancer, but Doubles Stroke Risk

Results of a randomized trial show that tibolone (Livial, Organon), approved for treatment of menopausal symptoms, has positive effects on fracture, breast cancer, and possibly colon cancer in women with osteoporosis over the age of 60 years but more than doubled the risk for stroke.

Read more: Tibolone Decreases Fracture, Breast Cancer, but Doubles Stroke Risk

Almost All Articles On Cancer Prognostic Markers Report Statistically Significant Results

Almost All Articles On Cancer Prognostic Markers Report Statistically Significant Results: Commentary from F1000

Kyzas PA, Denaxa-Kyza D, Ioannidis JP

Eur J Cancer 2007 Nov 43(17):2559-79

Commentary from Faculty Member Willi Sauerbrei


This is a landmark review illustrating the severity of reporting bias in prognostic marker research. The article impressively illustrates one of the most severe weaknesses of cancer prognostic marker research. Altogether more than 1900 articles were assessed, of which only 26 articles were fully 'negative'.

 

Read more: Almost All Articles On Cancer Prognostic Markers Report Statistically Significant Results

Transoral Incisionless Fundoplication May Prove Effective for GERD

Transoral incisionless fundoplication (TIF) provides safe and durable antireflux therapy in a canine model, according to a report in the July Annals of Surgery.

Read more: Transoral Incisionless Fundoplication May Prove Effective for GERD

Sentinel Node Dissection Before Preoperative Chemotherapy Improves Staging

In breast cancer patients with clinically node-negative disease, sentinel lymph node dissection (SLND) before preoperative chemotherapy is associated with accurate staging of the axilla, according to a report in the Archives of Surgery for July.

Read more: Sentinel Node Dissection Before Preoperative Chemotherapy Improves Staging

Amount: 

Color I Color II Color III

Log In or Register