Use of a chemofluorescence technique may allow surgeons to visualize, in real time, cancerous tissue, thereby increasing the precision of their resections, according to animal study findings presented Tuesday at the National Meeting of the American Chemical Society in Philadelphia.
Elevated free plasma DNA is a reliable indicator of recurrent esophageal cancer, more so than carcinoembryonic antigen (CEA), and is able to detect recurrent disease in most patients before clinical evidence emerges. These findings come from a study by researchers at the University of Southern California, published in the July issue of the Journal of the American College of Surgeons.
A new review by three renowned experts in cardiology suggests that efforts to treat elevated cholesterol levels are not exploiting the full potential of cholesterol-lowering strategies, and current approaches to treatment are simply doing "too little, too late. " The evidence, say these experts, is strong enough to support even more aggressive use of lipid-lowering therapies and to intervene at earlier stages in the development of atherosclerosis.
Polyalkylimide implants (PAI) used as dermal fillers can infrequently result in delayed and recurrent chronic inflammatory and granulomatous reactions, according to the results of a study published in the May issue of the Archives of Dermatology.
In patients undergoing liver resection for hepatocellular carcinoma related to hepatitis B virus (HBV) infection, viral load at the time of surgery is predictive of hepatoma recurrence, according to Chinese researchers.
Men with organ-confined prostate cancer and a Gleason score of 6 or less very rarely have local or biochemical recurrence of disease 5 years after prostatectomy, according to study findings appearing in the July issue of Urology.
Results of a randomized trial show that tibolone (Livial, Organon), approved for treatment of menopausal symptoms, has positive effects on fracture, breast cancer, and possibly colon cancer in women with osteoporosis over the age of 60 years but more than doubled the risk for stroke.
Almost All Articles On Cancer Prognostic Markers Report Statistically Significant Results: Commentary from F1000
Kyzas PA, Denaxa-Kyza D, Ioannidis JP
Eur J Cancer 2007 Nov 43(17):2559-79
Commentary from Faculty Member Willi Sauerbrei
This is a landmark review illustrating the severity of reporting bias in prognostic marker research. The article impressively illustrates one of the most severe weaknesses of cancer prognostic marker research. Altogether more than 1900 articles were assessed, of which only 26 articles were fully 'negative'.
In breast cancer patients with clinically node-negative disease, sentinel lymph node dissection (SLND) before preoperative chemotherapy is associated with accurate staging of the axilla, according to a report in the Archives of Surgery for July.